Endocrine Abstracts

Statins are cholesterol-lowering drugs decreasing bone resorption by inhibition of the farnesyl diphosphate synthase step in the mevalonic acid pathway and therefore are believed to have beneficial effects on bone status. Objective is to examine the relationship between lipid status and duration of statin therapy on the bone metabolism in dyslipidemic patients. A hundred and sixty subjects were divided into five groups depending on duration of statin therapy: (controls 0 years...